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SIMULATE THE HUMAN TISSUE MICROENVIRONMENT
Nortis provides an efficient, affordable alternative to animal testing that can accelerate research and advance scientific exploration. By supporting fluid flow, 3D tissue culture, and robust analysis in one scalable, user-friendly platform, Nortis offers a flexible approach to drive human health research and drug development.
NORTIS INNOVATION MAKES IT EASY TO:
- Engineer a variety of 3D tissue microenvironments
- Expose engineered tissues to flow and shear force via fluidic perfusion
- Perform real-time visualization under variable conditions
- Research human disease without relying on interspecies extrapolation
Small, disposable chips and perfusion hardware enable creation of various human tissue microenvironments for relevant insight into the world's most challenging biological questions. These tools are designed to serve a variety of applications, including:
Engineer, perfuse, and observe living human microvasculature
Reproduce functional units of specific organs
Confocal microscopy of a microvessel grown from human endothelial cells in a Nortis chip. The cell boundaries are labeled in green, the nuclei in blue. The red label is associated with laminin, indicating that the cells are depositing a basement membrane around the vessel.
Dr. Benjamin (Beno) Freedman of University of Washington (c) 2016 National Kidney Foundation